2024 Published Research

Collection of books on a shelf

The Charles E. Schmidt College of Medicine research programs span a variety of disciplines including healthy aging, geriatrics, neuroscience, chronic pain, opioid use, genomics, and precision medicine.

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October

September

  • Dunn J†, Davis BR, Matarazzo A†, Willett Y, Al-Farauki S, Maki DG, Hennekens CH . New clinical and public health challenges in vaccinations in US adults. Am J Med. 2024 Sep 30: S0002-9343(24)00620-X. doi:10.1016/j.amjmed.2024.09.025. Epub ahead of print. PMID: 39357693.
  • Hennekens CH , Sherling DH, Caceres A^, Benson K^, Rubenstein A, Ferris AH , Kitsantas P , Wood SK. Navigating the Global Pandemic in Pediatric Overweight and Obesity: Emerging Challenges and Proposed Solutions. Matern Child Health J. 2024 Sep 24. doi: 10.1007/s10995-024-04001-6. Epub ahead of print. PMID: 39316253.
  • Sacca L , Wilson C^, Hopkins DK, Kitsantas P , Densley S^, Lobaina D^, Peters D^, Branstetter B^, Clelland-Goddard ^A, Craig C^. HPV Vaccination Rates in Military Females: The Need for a Multi-Level and Evidence-Based Approach. Am J Health Promot. 2024 Sep 9:8901171241282579. doi:10.1177/08901171241282579. Epub ahead of print. PMID: 39250618.
  • Sacca, L. , Zerrouki, Y. †, Burgoa, S. †, Okwaraji, G. †, Li, A. †, Arshad, S. †, Gerges, M. †, Tevelev, S. †, Kelly, S. †, Michelle Knecht , Panagiota Kitsantas , Laurie Scott, Robert Hunter, Alexis Piccoli, Gabriela Colon, Michele Retrouvey (2024). Exploring Measurement Tools Used to Assess Knowledge, Attitudes, and Perceptions of Pregnant Women Toward Prenatal Screening: A Systematic Review. Women’s Health (Lond). 2024 Jan-Dec; 20:17455057241273557. doi:10.1177/17455057241273557. PMID: 39206551; PMCID: PMC11363050.
  • Bautista, A., Jacomino, M. , Peters, D.†, Fridman, S ‡, Luck, G . Rest in Peace or in Pieces: Post-Mortem Care Options in U.S. Advance Directives. J Appl Gerontol. 2024 Sep 18:7334648241282817. doi:10.1177/07334648241282817. Epub ahead of print. PMID: 39291783.
  • Rodriguez P^, Kalia V, Fenollar-Ferrer C, Gibson CL∆, Gichi Z, Rajoo A, Matier CD, Pezacki AT, Xiao T, Carvelli L , Chang CJ, Miller GW, Khamoui AV, Boerner J, Blakely RD . Glial swip-10 controls systemic mitochondrial function, oxidative stress, and neuronal viability via copper ion homeostasis. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2320611121. doi:10.1073/pnas.2320611121. Epub 2024 Sep 17. PMID: 39288174.

August

  • Sacca L , Lobaina D, Knopf E, Burgoa S, Jimenez S, Okwaraji G, Etzel M, Vardanyan V, Tharp M, Rao M, Jhumkhawala V, Sohmer J, Densley S, Linzer N, Meka P, Diaz D, Knecht M , Hopkins DK, Kitsantas P , Mejia MC , Wilson C. Assessment of the Validity and Quality of Polycystic Ovarian Syndrome (PCOS) Screening Tools Available for Women Globally: A Systematic Review. Clin Pract. 2024 Aug 23;14(5):1625-1649. doi: 10.3390/clinpract14050131. PMID: 39311281; PMCID: PMC11417729.
  • Shih RD , Engstrom G, Pandya AS, Fields GB, Furht B, Danesh AA, Alter SM , Munoz H, Clayton LM , Solano JJ , Buckley T , Hung O, Farag A, Wells M . Pharmacogenomic Drug-Gene Interactions in Geriatric Emergency Department Patients That Have Fallen. medRxiv. 2024.08.14.24311970; doi:10.1101/2024.08.14.24311970.
  • Kitsantas P , Benson K, Knecht M , Al-Farauki S, Hennekens CH , Learman L: Emerging diagnostic tools for early diagnosis of  endometriosis. Rep Med Gyn & Ob, 2024 Aug 12, Published online
  • Luck GR , Bautista A, Peters D†, Attonito J, Fridman S‡, Sohmer J†, Jacomino M . Advance Directives Revisited (2002 vs. 2023): Are We Closer to Uniformity?, The Gerontologist, 2024; gnae103, doi: 10.1093/geront/gnae103
  • Refai Oˣˣ, Rodriguez P^, Gichi Z, Blakely RD . Forward genetic screen of the C. elegans million mutation library reveals essential, cell-autonomous contributions of BBSome proteins to dopamine signaling. J Neurochem. 2024 Aug 8. doi:10.1111/jnc.16188. Epub ahead of print. PMID: 39118406.
  • Mohler, R. †, Lotharius, K. †, Moothedan, E. †, Bandi, R. †, Goguen, J. †, Beaton, R. †, Mejia, M. , Khoury, M., Sacca, L. Factors Contributing to Diabetic Ketoacidosis Readmission in Hospital Settings in the United States: A Scoping Review. Journal of Diabetes and Its Complications. 2024 Aug 8;38(10):108835. doi:10.1016/j.jdiacomp.2024.108835. Epub ahead of print. PMID: 39137675.
  • Rao, M. †, Densley, S. †, Marciniak, A. †, Burgoa, S. †, Zerrouki, Y. †, Okwaraji, G. †, Lobaina, D. †, Jhumkhawala, V. †, Knecht, M. , Kitsantas, P. , Sacca, L. Dissemination and Implementation Science Frameworks and Strategies to increase breast cancer screening and sufficient follow-up for affected women in the United States: A Systematic Review. Journal of Public Health Research. 2024 Aug 5;13(3):22799036241268841. doi:10.1177/22799036241268841. PMID: 39119619; PMCID: PMC11304495.
  • Attonito J, Freeman K , Bone MK, Howard H, Blum B, Luck G (August 04, 2024). Knowledge, Attitudes, and Beliefs Regarding Medical Cannabis Among Patients and Providers in Florida’s Long-Term Care Facilities. Cureus 16(8): e66115. doi:10.7759/cureus.66115

July

  • Davis BR, Hennekens CH , Greenwald J., Dunn J, Matarazzo A†, Benson K†, Kitsantas P , Rubin S. New clinical challenges in uncontrolled hypertension: The old silent killer is still alive and well. Am J Med. 2024 Jul 30:S0002-9343(24)00472-8. doi:10.1016/j.amjmed.2024.07.005. Epub ahead of print. PMID: 39089434.
  • Lotharius KC†, Finley CA, Averkiou P (July 26, 2024). Social-Emotional Development in the Summer Art Camp Setting. Cureus 16(7): e65448. doi:10.7759/cureus.65448
  • Hagan, V‡, Myers E†,  Caussat T‡, Sobhan A*, Barrueto L*, Awan A (July 21, 2024). Atypical Cutaneous Manifestation of Mycosis Fungoides: A Case Report. Cureus 16(7): e65034. doi:10.7759/cureus.65034
  • Caussat T‡, Kong H†, Macknofsky B†, Mann A, Rueda M, Borrego R (July 20, 2024). Testicular Torsion as a Complication Following Preperitoneal Packing for Pelvic Fractures in a Motorcycle Accident: A Case Report. Cureus 16(7): e64996. doi:10.7759/cureus.64996
  • Machi JF , Altilio I, Qi Y, Morales AA, Silvestre DH, Hernandez DR, Da Costa-Santos N, Santana AG, Neghabi M, Nategh P, Castro TL, Werneck-de-Castro JP, Ranji M, Evangelista FS, Vazquez-Padron RI, Ernesto Bernal-Mizrachi E and Rodrigues CO . Endothelial c-Myc knockout disrupts metabolic homeostasis and triggers the development of obesity. Frontiers in Cell and Developmental Biology. 2024 Jul 19;12:1407097 doi:10.3389/fcell.2024.1407097. PMID: 39100099; PMCID: PMC11294153.
  • †Arthur Pavlovsky, †Camryn R. Marshall, †Samantha Braud, †Everett J. Kim, Mario Jacomino (July 19, 2024). Chromosomal 1p Duplication in a Pediatric Patient: A Case Report. Cureus 16(7): e64911. doi:10.7759/cureus.64911
  • Kushner JN†, Swickley T†, Bandi R†, Lian J, Knecht MK , Sacca L . Examining the Prevalence of Anterior Cruciate Ligament Injuries on Artificial Turf Surfaces Compared to Natural Grass Surfaces in Athletes: A Scoping Review. Cureus. 2024 Jul 3;16(7):e63770. doi: 10.7759/cureus.63770. PMID: 39099910; PMCID: PMC11296738.
  • American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Seizures; Smith MD, Sampson CS, Wall SP, Diercks DB; Members of the American College of Emergency Physicians Clinical Policies Committee (Oversight Committee); Diercks DB, Anderson JD, Byyny R, Carpenter CR, Friedman BW, Gemme SR, Gerardo CJ, Godwin SA, Hahn SA, Hatten BW, Haukoos JS, Kaji A, Kwok H, Lo BM, Mace SE, Mattu A, Moran M, Promes SB, Shah KH, Shih RD , Silvers SM, Slivinski A, Smith MD, Thiessen MEW, Thompson JT, Tomaszewski CA, Trent SA, Valente JH, Westafer LM, Wall SP, Yu Y, Finnell JT, Schulz T, Vandertulip K. Clinical Policy: Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Seizures: Approved by the ACEP Board of Directors, April 17, 2024. Annals of Emergency Medicine. 2024;84(1):e1-e12. doi:10.1016/j.annemergmed.2024.02.018. PMID: 38906639.
  • Zirulnik A, Liu S, Wells M , Alter SM , Engstrom G, Solano JJ , Clayton LM , Reiter M, Hughes PG, Goldstein L, Shih RD . Alcohol use is associated with intracranial hemorrhage in older emergency department head trauma patients. Journal of the American College of Emergency Physicians Open. 2024 Jul 31;5(4):e13245. doi:10.1002/emp2.13245. PMID: 39086794 ; PMCID: PMC11289673.
  • Shih RD , Alter SM , Wells M , Solano JJ , Engstrom G, Clayton LM , Hughes PG, Goldstein LN, Lottenberg L, Ouslander JG . The Florida Geriatric Head Trauma CT Clinical Decision Rule. Journal of the American Geriatrics Society. 2024 Jul 3. doi:10.1111/jgs.19057. Epub ahead of print. PMID: 38959158.
  • Lo AX, Shih RD , Rackman AS , Kennedy RE. Challenges for emergency departments: Anti-amyloid therapy and amyloid-related imaging abnormalities in persons with dementia. Journal of the American Geriatrics Society. 2024 July 22. doi:10.1111/jgs.19099. Epub ahead of print. PMID: 39036948.

June

  • Clayton L , Wells M , Alter S , Solano J , Hughes P, Shih R . Educational concepts: A longitudinal interleaved curriculum for Emergency Medicine residency training. Journal of the American College of Emergency Physicians Open. 2024 Jun 20;5:e13223. doi:10.1002/emp2.13223. PMID: 38903766; PMCID: PMC11187808.
  • Sacca, L. , Okwaraji, G. †, Densley, S. †, Marciniak, A. †, Knecht, M. , Wilson, C., Pilitsis, J., & Hopkins, D.K. Polycystic ovary syndrome and chronic pain among females and individuals of childbearing age. A Scoping Review. Sage Open Medicine, 2024 Jun 19;12:20503121241262158. doi:10.1177/20503121241262158. PMID: 38903491; PMCID: PMC11189018.
  • Shih RD , Alter SM , Solano JJ , Engstrom G, Wells M , Clayton LM , Hughes PG, Goldstein LN, Azar F, Ouslander JG. Low Incidence of Delayed Intracranial Hemorrhage in Geriatric Emergency Department Patients on Preinjury Anticoagulation Presenting with Blunt Head Trauma. J Emerg Med. 2024 June 13:S0736-4679(24)00188-4. doi:10.1016/j.jemermed.2024.06.002.  Epub ahead of print. PMID: 39271405.
  • Expert Panel on Neurological Imaging; Wang LL, Thompson TA, Shih RY, Ajam AA, Bulsara K, Burns J, Davis MA, Ivanidze J, Kalnins A, Kuo PH, Ledbetter LN, Pannell JS, Pollock JM, Shakkottai VG, Shih RD , Soares BP, Soderlund KA, Utukuri PS, Woolsey S, Policeni B. ACR Appropriateness Criteria® Dizziness and Ataxia: 2023 Update. Journal of the American College of Radiology. 2024;21(6S):S100-S125. doi:10.1016/j.jacr.2024.02.018. PMID: 38823940.

May

April

  • Sacca, L. , Lobaina, D.*, Burgoa, S.*, Lotharius, K.*, Moothedan., E.*, Gilmore, N.*, Xie, J.*,Mohler, R.*, Scharf, G.*, Knecht, M. , Kitsantas, P. Promoting artificial intelligence for global breast cancer risk prediction and screening in adult women: A scoping review. Journal of Clinical Medicine. 2024 Apr 25;13(9):2525. doi:10.3390/jcm13092525. PMID: 38731054; PMCID: PMC11084581.
  • Lee JE, Murchison K, Hassanein L, Peters D, Jacomino M, Luck G . Trends in HIV-Related Services Offered by Substance Abuse Treatment Facilities. Cureus. 2024 Apr 1;16(4):e57400. doi:10.7759/cureus.57400. PMID: 38694649; PMCID: PMC11062491.
  • Ejezie CL, Choi J, Ayieko S, Burgoa S†,, Zerrouki Y†,, Lobaina D†,, Okwaraji G†,, Defeu S, Sacca L . Digital Health Interventions for Cancer Prevention Among Racial and Ethnic Minority Groups in the United States: A Scoping Review. J Racial Ethn Health Disparities. 2024 Apr 8. doi:10.1007/s40615-024-01958-6. Epub ahead of print. PMID: 38587751.

March

  • Mesa H, Meade J, Gajewski-Kurdziel P XX , Blakely RD , Zhang Q. Simple Rescue of Opaque Tissue Previously Cleared by iDISCO. Bio Protoc. 2024 Mar 5;14(5):e4948. doi:10.21769/BioProtoc.4948. PMID: 38464943; PMCID: PMC10917697.
  • Kitsantas, P., Aljoudi, S. ^ M., & Sacca, L. (in press). Perception of risk of harm from cannabis use among women of reproductive age with disabilities. Cannabis and Cannabinoid Research. March 2024 PMID: 38442223 doi:10.1089/can.2023.0199
  • Kitsantas, P., Mejia, M. C., Sewak, R., Sacca, L., & Hennekens, C.H. (in press). Vibroacoustic therapy to treat pain in the temporomandibular joint Medical Hypothesis. March 2024 doi:10.1016/j.mehy.2024.111321

  • Schwartz S*, Goldman E*.  A Deadly Case of Invasive Aspergillosis.  Presented at Florida American College of Physicians Meeting, Orlando, FL, March 23, 2024.

  • Collamore G†, DiCorcia MJ , Nagpal Y†, Fiedler L, Garone MA, DeMets DL, Maki DG, Hennekens CH . Guidance for healthcare providers on newest guidelines for over-the-counter drug treatment of mild symptoms of COVID-19. Am J Med. 2024 Mar 13:S0002-9343(24)00140-2. doi:10.1016/j.amjmed.2024.03.003. Epub ahead of print. PMID: 38490308.

  • Rubin SP . (2024) “Gay Health”. In Domino FJ, Baldor RA, Barry KA, Golding J, Stephens MB. (eds.) The 5-Minute Clinical Consult 2024. 32nd ed. 12 June 2023. Wolters Kluwer.

February

  • Gaudet ID^, Xu H, Gordon E†, Cannestro GA^, Lu ML, Wei J . Elevated SLC7A2 expression is associated with an abnormal neuroinflammatory response and nitrosative stress in Huntington's disease. J Neuroinflammation. 2024 Feb 28;21(1):59. doi:10.1186/s12974-024-03038-2. PMID: 38419038; PMCID: PMC10900710.

  • Lee CD, Imran I^, Thomas S^, Nouri-Shirazi M. A comprehensive method for the phenotypical and functional characterization of recalled human memory B and T cells specific to vaccine antigens. J Immunol Methods. 2024 Feb 28;527:113650. doi:10.1016/j.jim.2024.113650. Epub ahead of print. PMID: 38428517.

  • Sherling DH, Hennekens CH, Ferris AH. Newest updates to health providers on the hazards of ultra-processed foods and proposed solutions. Am J Med. 2024 Feb 9:S0002-9343(24)00069-X. doi:10.1016/j.amjmed.2024.02.001. Epub ahead of print. PMID: 38342198.
  • Jhumkhawala, V.†, Lobaina, D.†, Okwaraji, G.†, Zerrouki, Y.†, Burgoa, S †, Marciniak, A.†, Densley, S.†, Rao, M †, Diaz, D.*, Knecht, M. , Sacca, L.  Social determinants of health and health inequities in breast cancer screening: a scoping review. Frontiers in Public Health. 2024 Feb 6:12. doi:10.3389/fpubh.2024.135471
  • Doumat G., Choudhury, S., Doumat, N., Idriss, A∆ & Sacca, L. (2024). Assessing Physical, Mental, and Social Factors Associated with Refugee Children Food Insecurity, Food Relief Barriers, and Lessons Learned in the Middle East and North Africa (MENA) Region: A Scoping Review. Journal of Hunger & Environmental Nutrition. doi:10.1080/19320248.2024.2310505.
  • Bommareddy A , Oberlin J, Blankenhorn K, Hughes S, MabryE, Knopp A, VanWert A, Dwivedi C, Pinkerton I and Gutierrez L. Alpha-santalol, a derivative of sandalwood oil prevents development of prostate cancer in TRAMP mice, Phytomedicine Plus. Feb 2024: 100523, Vol 4, Issue 1. doi:10.1016/j.phyplu.2024.100523.

January

  • Merugu R+, Duval K*, Gutman D, Wilson J.  Disseminated Cryptococcus Mimicking Hepatitis.  Presented virtually at Florida American College of Physicians Medical Student and Resident Poster Competition, January 2024. 

  • Ceyhan B, Nategh P, Neghabi M, LaMar JA∆, Konjalwar S, Rodriguez P^, Hahn MK, Gross M, Grumbar G, Salleng KJ, Blakely RD , Ranji M. Optical Imaging Demonstrates Tissue-Specific Metabolic Perturbations in Mblac1 Knockout Mice. IEEE J Transl Eng Health Med. 2024 Jan 15;12:298-305. doi:10.1109/JTEHM.2024.3355962. PMID: 38410184; PMCID: PMC10896421.
  • Oleinikov AV , Seidu Z, Oleinikov IV, Tetteh M, Lamptey H, Ofori MF, Hviid L, Lopez-Perez M. Profiling the PfEMP1-specific IgG response among Ghanaian children with hemoglobin S and C. J. Infect. Dis. 2024 Jan 12;229(1): 203-213. doi:10.1093/infdis/jiad438. PMID: 37804095; PMCID: PMC10786258.
  • Rusali LE, Lopez-Hernandez AM, Kremiller KM, Kulkarni GC, Gour A, Straub CJ, Argade MD, Peters CJ, Sharma A, Toll L , Cippitelli A , Riley AP. Synthesis of α3β4 Nicotinic Acetylcholine Receptor Modulators Derived from Aristoquinoline That Reduce Reinstatement of Cocaine-Seeking Behavior. J Med Chem. 2024 Jan 11;67(1):529-542. doi:10.1021/acs.jmedchem.3c01758. Epub 2023 Dec 27. PMID: 38151460.
  • Hennekens CH ,  Mitchell J^, Dumpa M†, Maki DG, DiCorcia M , Levine RS, Mejia M. Emerging data on COVID-19 create urgent challenges for health providers: Updates on COVID-19 vaccine and Paxlovid.  J Natl Med Assoc. 2024 Jan 12:S0027-9684(24)00004-X. doi:10.1016/j.jnma.2024.01.007. Epub ahead of print. PMID: 38218693.

  • Gajeswski-Kurdziel PA, Walsh AE^, Blakely RD . Functional and pathological consequences of being fast on the uptake: Protein kinase G and p38α MAPK regulation of serotonin transporters. Curr Res Physiol. 2024 Jan 4;7:100117. doi:10.1016/j.crphys.2024.100117. PMID: 38298474; PMCID: PMC10825370.

  • Ke T, Ambigapathy G, Ton T, Dhasarathy A, Carvelli L. Long-Lasting Epigenetic Changes in the Dopamine Transporter in Adult Animals Exposed to Amphetamine during Embryogenesis: Investigating Behavioral Effects. Int J Mol Sci. 2023 Aug 23;24(17):13092. doi:10.3390/ijms241713092. PMID: 37685899; PMCID: PMC10487411.
  • Bhandari S^, Xu H, Chen B∆, Basilio S∆, Sartipi P^, Sontag H^, Shen W , Tao R , Prentice H , and Wu J.Y. Assessing Behavioral and Psychological Symptoms of Dementia in a 3xTg-AD Mouse Model of Alzheimer’s Disease. Open Access J Neurol Neurosurg 2023; 18(5): OAJNN.555996. doi:10.19080/OAJNN.2023.18.555996
  • Chin A*, Bastaich DR, Dahman B, Kaplan DE, Taddei TH, John BV. Refractory hepatic hydrothorax is associated with increased mortality with death occurring at lower MELD-Na compared to cirrhosis and refractory ascites. Hepatology. 2023 Aug 25. doi:10.1097/HEP.0000000000000577. Epub ahead of print. PMID: 37625139.
  • American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Severe Agitation; Thiessen MEW, Godwin SA, Hatten BW, Whittle JA, Haukoos JS, Diercks DB; Members of the American College of Emergency Physicians Clinical Policies Committee (Oversight Committee); Diercks DB, Wolf SJ, Anderson JD, Byyny R, Carpenter CR, Friedman B, Gemme SR, Gerardo CJ, Godwin SA, Hahn SA, Hatten BW, Haukoos JS, Kaji A, Kwok H, Lo BM, Mace SE, Moran M, Promes SB, Shah KH, Shih RD , Silvers SM, Slivinski A, Smith MD, Thiessen MEW, Tomaszewski CA, Valente JH, Wall SP, Westafer LM, Yu Y, Cantrill SV, Finnell JT, Schulz T, Vandertulip K. Clinical Policy: Critical Issues in the Evaluation and Management of Adult Out-of-Hospital or Emergency Department Patients Presenting With Severe Agitation: Approved by the ACEP Board of Directors, October 6, 2023. Ann Emerg Med. 2024 Jan;83(1):e1-e30. doi:10.1016/j.annemergmed.2023.09.010. PMID: 38105109.
  • Sotis CL, Jafari H, Solano JJ , Fishman I. Transient Hypoglossal and Lingual Nerve Injury Following the Use of I-gel Supraglottic Airway: A Case Report. Cureus. 2023 Oct 23;15(10):e47509. doi:10.7759/cureus.47509. PMID: 38021847.
  • Wells M , Goldstein LN, Alter SM , Solano JJ , Engstrom G, Shih RD . The accuracy of total body weight estimation in adults – A systematic review and meta-analysis. AM J Emerg Med. 2024 Feb;76:123-135. doi:10.1016/j.ajem.2023.11.037. Epub 2023 Nov 29. PMID: 38056057.

Legend

^ current graduate student (MS/PhD)
∆ graduated graduate student (MS/PhD)
† current medical student
‡ graduated medical student
* current resident
** graduated resident
ˣ current postdoctoral fellow
ˣˣ former postdoctoral fellow
BOLD - COM Faculty member

Published Research Archive

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